The mid－to－long term follow－up of Graves disease after interventional embolization<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

杨建勇　庄文权　陈伟　李鹤平　李维多

YANG Jianyong，ZHUANG Wenquan，CHEN Wei，LI Hepin.，LI Weiduo，Department of Radiology，The first hospital of Zhongshan University，Guangzhou 510080，China

Abstract

　　Objective：To explore the mid－to－long term therapy efficacy of Graves’ disease after interventional embolization.

　　Methods：25 patients of Graves’ disease underwent interventional embolization have been followed up for 2－4 years. T3，T4 have been monitored pr－operation，six months，12 moths，2，3，4 years respectively. Other references included：pulse，thyroid size and vessel’s murmur.

　　Results：22 patients have completely relieved from the hyperthyroidism during the follow－up. Only one patient suffered recurrence. Other two patients were still on maintaining dosage of antithyroid drug therapy. No hypothyroidism or hypoparathyroidism has been found during this term.

　　Conclusion：Mid－to－long term follow－up showed satisfactory efficacy of interventional therapy，offering another alternative for treatment of refractory Graves’ disease.

　　Key words：Graves disease；Embolization，therapeutic；Treatment outcome；Evaluation studies

　　弥漫性甲状腺肿伴甲状腺功能亢进（Graves病）是较常见的1种自身免疫性疾病。女性人群中患病率可高达1.9％，以中青年最为常见，且近年来有逐渐增高的趋势。李金明等^[1]1992年将甲状腺动脉栓塞术应用于犬甲亢的实验研究以来，国内外学者进行了初步的临床应用研究。但介入治疗的中远期随访观察文献报道较少。我院自1997年1月开展Graves病的介入治疗以来，对25例患者进行了动脉栓塞后2～4年的中长期随访，笔者拟对介入治疗Graves病的中远期疗效作一分析。