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In Vitro Simulation and Verification of Implanted Microwave Thermal Distribution in Pig Liver
Liong Ping ，Dong Baowei，Yu Xiaoling，Yu Dejiang ，Cheng Zhigang，Su Li，Peng Jianshu，Nan Qun．Wang Huai， Dang Ying(Dept．of Ultrasound，Chinese PLA General Hospital，Beijing 100853)
【ABSTRACT】Purpose：To investigate feasibility of using computer simulation of thermal distribution of implant d microwave radiation under ultrasound guidance in pig liver．Materials and Methods：Thermal coagulated area and thermal distribution at clinically used power output were calculated and verified by computer simulation． Thermphysical properties of pig liver had been obtained in previous experiment. Thermal distributions pig liver were reconstructed via computer simulation． The accuracy of the thermal distribution of simulation was tested and verified by real measurement at 496 points(times)of 26 pig livers in vitro experiments .Results：The concordance rates between measured temperature curves and computer simulation curves were 88.91％ The coagulated areas after microwave radiation in pig liver coincided with that of computer simulation at temperature of 54℃ ．Conclusion：The result in predicting microwave thermal distribution with computer simulation is a reliable method．It could he used to simulate in vivo thermal distributions．
Key words microwave thermal therapy；liver；computer simulation；interventional ultrasound
本研究较深入地研究了用计算机模拟与测量超声引导下经皮微波治疗肝癌生物热场的分布 根据体模实验，可以精确布置测温点，得到准确详细的组织比吸收率(SAR)和计算机模拟温度场的分布[1]．但体模在高温下脱水变性，使实测温度与计算机模拟的温度值出现偏差，为验证计算机模拟微波热场的准确性，我们用离体猪肝进行了一系列实验研究。
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