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Evaluation of left ventricular structure and function with echocardiography after acute myocardial infarction
刘望彭 王宏宇 李玉梅 康春松 陈武 李天亮
LIU Wangpeng, WANG Hongyu, LI Yumei, et al.
Abstract
Objective: To observe left ventricular structure and function change, evaluate the impact of thrombolytic therapy on the left ventricular structure and function after acute myocardial infarction continuously.
Methods: Echocardiography was applied to observe 28 cases of first acute myocardial infarction in the 4th week and the 12th week after infarction, left ventricular end-diastolic volume index (LVEDVI), left ventricular end-systolic volume index (LVESVI) and ejection fraction (EF) were measured. Results LVEDVI, LVESVI of all 28 cases were higher in the 12th weeks than in the 4th weeks (P<0.01, P<0.05). Compared two examination
Results: LVEDVI and LVESVI had no significant difference (P>0.05), EF was higher in thrombolytic (P<0.05) ; LVEDVI and LVESVI were higher in nonthrombolytic (P<0.05) and anterior wall infarction group (P<0.01); LVEDVI, LVESVI and EF had no significant changes (P>0.05) in inferior wall infarction.
Conclusions: Left ventricular structure would change after acute myocardial infarction. Thrombolytic therapy could prevent left ventricle from dilating. Echocardiography is a useful method in evaluating left ventricular structure and function after acute myocardial infarction. key words: Echocardiography Myocardial infarction Ventricular function, left
急性心肌梗塞后由于心肌细胞坏死导致整体心脏功能的下降,随着坏死心肌的吸收,局部胶原沉积,疤痕形成,在梗塞区和非梗塞区将发生进行性的扩张。这种开始于急性心肌梗塞的早期,并持续几个月甚至几年的左室扩大,称为急性心肌梗塞后的左室重构[1,2]。许多研究结果表明急性心肌梗塞后的左室重构是影响患者心功能及远期预后的重要因素。本研究旨在应用超声心动图观察急性心肌梗塞后左室结构和功能的动态变化,评估溶栓治疗对急性心肌梗塞后左室结构和功能的影响。
资料与方法
首发急性心肌梗塞患者28例,其中男27例,女1例,平均年龄(61.0±9.2)岁,所有患者均符合1980年第一届内科学术会议心血管专业组建议使用的WHO对冠心病急性心肌梗塞的诊断标准[3]。其中溶栓治疗组16例,未溶栓组12例;前壁梗塞组20例,下壁梗塞组8例。对28例患者在第4周及第12周时进行心梗后超声心动图检查。仪器为美国HP-1000型彩色多普勒超声心动图检查仪,探头频率2.5MHz;北京科力新技术发展公司BIE-2020型超声心动图图像处理系统。
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