超声显像观察肝脏柔软度变化对慢性肝炎和早期肝硬化鉴别诊断的作用
|
时间:2009-01-13 18:42:33 来源: 作者: |
|
Role of ultrasound imaging observation of changes in liver flexibility in diagnosing chronic hepatitis and early liver cirrhosis
CHEN Zhi-hua,BAI Jiao,LEI Lin,et al.Department of Ultrasound,Shiyan Peoples Hospital,Shiyan 442000,China
[Abstract] Objective To explore the clinical value of ultrasound imaging observation of changes in the liver flexibility in diagnosing chronic hepatitis and early liver cirrhosis.Methods Ultrasound showed:Second porta hepatis view;IVC left liver lobe sagittal view;AA left liver lobe sagittal view,semi-quantitative observations deformation rate of liver produced by the great vessels pulse.Results Deformation rate reflected the softness of the liver,flexibility in line with the pathological changes of the liver.Conclusions To observe liver softness change has certain significance to the chronic hepatitis and the early liver cirrhosis in differential diagnosis.
[Key words] ultrasonography;flexibility;chronic hepatitis;cirrhosis
慢性肝炎是以肝细胞坏死,炎性细胞浸润为主要病理改变,肝细胞增生,纤维组织增生不明显,大体标本见肝脏体积可缩小,包膜皱缩,质地柔软。慢性肝病随着病情的进展,逐步发展为肝纤维化,最终发展为肝硬化[1]。肝硬化是以肝细胞变性坏死,炎性细胞浸润,继而纤维组织增生(肝纤维化)和肝细胞结节性再生,这三种变化反复交错进行,结果使肝小叶结构和血液循环逐渐改变,使肝脏变性、变硬,大体标本可见肝脏缩小、质地逐渐变硬[2]。因此若能很好地观察肝质地柔软度变化,可很好分析肝病进展情况,超声通过二维显像可反映肝脏柔软度的改变。
1 资料与方法
1.1 一般资料 在我院就诊的2003~2007年不同期慢性肝病患者152例,男105例,女47例,年龄19~65岁,平均42.5岁,均做穿刺活检病理诊断。
1.2 方法 采用L7和V7彩色多普勒超声显像仪,探头频率3.5 MHz,被检者常规超声检查,重点显示第二肝门切面,显示三支肝静脉;经下腔静脉肝左叶矢状切面,显示肝左外叶与下腔静脉;经腹主动脉肝左叶矢状切面,显示肝左叶与腹主动脉及心脏。随着肝静脉、下腔静脉及腹主动脉的搏动,看肝脏与之交界处局部形变幅度,由于这种形变幅度均很小,无法精确测量,故将肝脏形变幅度半定量分为明显、可见、不明显和完全消失仅见整体运动;肝静脉、下腔静脉、腹主动脉及心脏的搏动,是依次增强的。因此,可依据上述三个切面中肝脏局部形变程度间接反映肝脏柔软度。所有患者均做穿刺活检,分析超声显像观察肝脏柔软度与肝炎病程变化的相关性。
|
|
|
|