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Observation of Clinical Effectiveness Via Interventional Treatment of Massive Hemoptysis Caused by Pulmonary Tuberculosis <?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />
陆普选* 朱文科* 蔡雄茂# 曹满瑞△
余卫业# 杨根东* 孙燕芝# 刘锦清*
LU Puxuan,ZHU Weike CAI xiongmao, et al. Department of Radiology, Shenzhen East Lake hospital ,Shenzhen, China 518020,
Abstract
Objective：To investigate the effect of bronchial artery infusion with Reptilase plus with or not target artery embolization in treatment of massive hemoptysis caused by pulmonary tuberculosis.
Methods：Among 34 patients with massive hemoptysis (≥600ml/24Hours) caused by pulmonary tuberculosis, 21 cases (group 1) were treated by bronchial artery infusion with Reptilase (1—3KU) plus target artery embolization with gelfoam sponge.13 cases (group 2) were treated only by bronchial artery infusion with Reptilase (1—3KU) due to inaccessible to the bleed target artery.
Results：32 of 34 cases (94.1%) in total were cured by this therapy, 2 cases (one in each group) needed further surgery treatment . Among the cured 34 cases, 32 cases received treatment for one time,1 cases 2 times and 1 case 3 times. There is no significant difference between the efficacy of treatment of group 1 and group 2 (P>0.05).
Conclusion：Bronchial artery infusion with Reptilase plus with or not target artery embolization is effective and safe method in therapy of massive hemoptysis caused by pulmonary tuberculosis. In case of inaccessible to target the bleed artery in lung, infusion with Reptilase (1—3KU) locally is an optional and useful to treat the hemoptysis.
Key words：Reptilase; bronchial artery; intervention/therapy; massive hemoptysis/pulmonary tuberculosis
介入放射学的开展，为肺结核大咯血的治疗开辟了有效的新途径，取得较为满意的效果[1.2.3]。由于支气管动脉的解剖变异较大，支气管动脉与肋间动脉和/或脊髓动脉共干者约占60℅[4]。因此，支气管动脉栓塞治疗肺结核大咯血，有时技术上受到一定限制，治疗效果受到影响。为提高肺结核大咯血治疗的有效率，我们对34例肺结核大咯血病人进行支气管动脉内应用立止血治疗，取得满意的疗效，现报告如下。 | 
