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The effect of endostatin gene in combination with radiotherapy on rats with implanted tumor
李勇 金宁 杨海山
LI Yong,JIN Ning,YANG Hai-shan,et al.
China-Japan Union Hospital of Ji lin University,Chang chun l30033,China
Abstract
Objective:To study the effect Of combinating Of the radiotherapy with endostatin gene therapy on the rats with implanted tumor.
Methods:lmmediate Walker-256 cancerous ascetic iniection method was used to make a rat tumor-bearing model,then the tumor was treated with saline,endostatin gene,irradiation or endostatin gene plus irradiation.The tumor growth rate and weight were observed,Western blot and RT-PCR were adopted to check the expressions of endostatin mRNA and protein. |