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The Effect of WBC Count on the Short-term and Long-term Prognosis in Acute Myocardial Infarction Patient Undertook Emergent-PCI<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />
陈 晖 贾三庆 严松彪 王雷
李虹伟 苏淑红 高红丽 王璐
范 纬 沈潞华
首都医科大学附属北京友谊医院心血管疾病诊治研究中心
北京 100050
Hui Chen, San-qing Jia, Song-biao Yan, et al.
Heart & Blood Vessel Center, Beijing Friendship Hospital,Capital Univercity of Medical Sciences, Beijing 100050, China
ABSTRACT
Objective: To observe the effect of white blood cell(WBC) count on the short-term and long-term prognosis in acute myocardial infarction patient undertook emergent-PCI.
Methods: A total of 352 consecutive acute myocardial infarction patients from Apr 2000 to Jan 2004 who undertook emergent-PCI were divided into three groups according to the WBC count: group 1(n=187, WBC≤10×109/L), group2 (n=139, 10×109/L <WBC≤15×109/L) and group3(n=26, WBC>15×109/L).The average age was 60.7±11.6 years(29-88ys), male cases 265, female cases 87, the average follow-up term is 26.8±12.1 months(6-51ms).
Results: Compared to group 1, the age was lower in group 2(P <0.05)and group 3(P <0.01),the ratio of hypertention history was lower in group 2 and group 3(P <0.05), the levels of CRP( P <0.05) and the peak values of CK(P <0.05)were higher in group2 and group 3, the lesion vessels numbers were lower in group 2 and group3(P <0.05 ), smoking history (P <0.05)and triglyceride level (P <0.01)was higher in group 2, CKMB level(P <0.05) was higher in group 3. Compared to group 1 and group2, the level of Killip Classification was higher in group 3(P <0.01). The correlation analysis showed that WBC count is significantly correlated with these following factors: age(correlation coefficient -0.214, P <0.001),hypertention (correlation coefficient -0.156, P <0.01), TG(correlation coefficient 0.112, P <0.05), CRP(correlation coefficient 0.194, P <0.05), CK(correlation coefficient 0.327, P <0.001), CKMB(correlation coefficient 0.198, P <0.001), Killip(correlation coefficient 0.185, P <0.01), Pacer(correlation coefficient 0.111, P <0.05), TIMI(correlation coefficient - 0.112, P <0.05), in-hospital morality(correlation coefficient 0.157, P <0.01),long-term morality(correlation coefficient 0.131, P <0.05).
Conclusion: The count of WBC was significantly correlated with CRP, CK, CKMB, Killip, TIMI, in-hospital and long-term morality, so it is a very good index to reflect damage of heart muscle and the short-term and long-term prognosis.
Key words: Acute myocardial infarction, White blood cell, Prognosis |
