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Assessing myocardial viability in patients with myocardial infarction by quantitative tissue velocity imaging during low-dose dobutamine stress<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />
毕小军 邓又斌 常青 白娇 刘红云 杨好意 刘娅妮 黎春雷
BI Xiao-Jun, DENG You-Bin, CHANG Qing, et al. Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Abstract
Objective：To assess myocardial viability in patients with myocardial infarction by quantitative tissue velocity imaging(QTVI) during low-dose dobutamine stress echocardiography(LDDSE).
Methods：Twenty patients with myocardial infarction underwent percutaneous transluminal coronary angioplasty(PTCA) or PTCA plus stent. LDDSE were performed before operation. QTVI was used to acquire the velocity and displacement curves of impaired myocardium before and during LDDSE and after operation. The strain(S) and strain rate(SR) of impaired myocardium were measured.
Results：In the group that myocardium was survived, both low-dose dobutamine stress and PTCA can significantly raise the SR and S of the impaired myocardium. At the end of low-dose (10μg·kg-1·min-1) dobutamine stress, the magnitudes of SR and S were significant higher than that at rest（SR：1.0±0.4s-1 vs 0.2±0.2 s-1, P＜0.01；S：0.1±0.05 vs 0.03±0.01, P＜0.01）. There was no significant difference between the magnitudes of SR and S at the end of low-dose dobutamine stress and those after PTCA（SR：1.0±0.4 s-1 vs 0.8±0.2 s-1, P＞0.05；S：0.1±0.05 vs 0.1±0.04, P＞0.05）. But in the group that myocardium was not survived, neither the low-dose dobutamine stress nor PTCA can significantly raise the SR and S of the myocardium.
Conclusions：QTVI can assess myocardial viability during LDDSE.
Key words：quantitative tissue velocity imaging, dobutamine, myocardial infarction, myocardial viability | 
