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经胸超声检测冠状动脉左前降支局部血流加速对诊断左前降支狭窄的作用

时间:2005-12-28 23:52:44  来源:  作者:

Value of acceleration flow in left anterior descending coronary artery for detection of coronary artery stenosis by transthoracic color Doppler echocardiography<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

 

陈斌 邓又斌 杨好意 阮燕菲 常青 毕小军 王红英

CHEN Bin, DENG You-bin, YANG Hao-yi, et al. 

Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

 

Abstract

Objective:To detect acceleration flow in the left anterior descending coronary artery and evaluate its value for the detection of coronary artery stenosis by transthoracic color Doppler echocardiography. 

Methods:Blood flow in the left anterior descending coronary arteries was examined in 45 patients by transthoracic color Doppler echocardiograph and multipoint pulse Doppler spectrums were recorded in the same segment, and then the ratio of the maximal peak diastolic velocity to the minimal peak diastolic velocity calculated.  The ratio≥1.5 was the cutoff value for the presence of localized acceleration flow. 

Results:There were 23 patients with localized acceleration flow examined by echocardiography. Among them, 20 were found to have luminal diameter stenosis (reduced for 60%- 98%) in the left anterior descending coronary arteries by coronary angiography. There were 22 patients without localized acceleration flow examined by echocardiography. Among them, 18 had no stenosis, 4 patients had serious stenosis (reduced for ≥95%) or occluded segments in the left anterior descending coronary arteries on coronary angiography. The ratio of the maximal peak diastolic velocity to the minimal peak diastolic velocity was significant higher in the patients with left anterior descending coronary artery stenosis than that in those without stenosis (1.9±0.3 vs 1.3±0.2, P<0.01) and it correlated significantly with left anterior descending coronary artery stenosis (r=0.77, P<0.01).  The specificity by using the ratio≥1.5 for stenosis detection was 85.7% (18/21), and the sensitivity was 83.3% (20/24). 

Conclusions:Transthoracic color Doppler echocardiography is a reliable noninvasive method to detect localized acceleration flow in the left anterior descending coronary artery stenosis and it is useful in the noninvasive diagnosis of stenosis in the left anterior descending coronary artery.

Key words:Echocardiography ; Doppler; Coronary disease

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