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Application of BOLD－fMRI quantitive analysis in motor cortex

龙莉玲 黄仲奎 赖铁强

广西医科大学第一附属医院放射科 广西南宁市双拥路6号 530021

Long LiLing ，Huang Zhongkui，Lai Tieqiang

（Department of Radiology，The First Affiliated Hospital of Gaungxi Medical University，Guangxi Nanning 537000，China）

Abstract

　　Objective：To observe change of the active volumes of motor cortex with bold oxygenation level dependent functional magnetic resonance imaging （BOLD－fMRI） quantitatively and evaluate normal motor cortex active characteritics and rehabilitation therapy of diseases adjoining motor cortex in pre－and post－therapy.

　　Materials and Methods：Patient group，15 patients whose having motor cortex lesion，and control group，20 normal volunteers， were performed fMRI in motor cortex，following up in patient group after therapy in 1～14 days，1 month and 3 months.

　　Results：Motor cortex active volumes on fMRI in control group appeared no significant differences between right hand and left hand ，left hand and both hands motor mode（p>0.05）. Motor cortex active volumes on fMRI in patient group shown increment among 1 month after therapy with significant differences comparing pre－and post－therapy（P<0.05）. The motor cortex active volumes on fMRI increased sharply in first 1－14 days while slowly increased after 1 and 3 months therapy.