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Correlation between spiral CT features of serosa invasion and expression Of MVD and nm23-H1 in colorectal carcinoma
张永高1 高剑波1 杨学华1 张谢夫2 张云汉3 郭 华1 陈学军1 周志刚1 杨晓鹏1 岳松伟1
(1.郑州大学一附院放射科,2.普外科,3.病理科,河南郑州 450052)
ZHANG Yong-gao,GAO Jian-bo,YANG Xue-hua,ZHANG Xie-fu,ZHANG Yun-han,GUO Hua,CHEN Xue-jun,ZHOU Zhi-gang,YANG Xiao-peng,YUE Song-wei
(Department of Radiology,the First Affiliated Hospital of <?xml:namespace prefix = st1 ns = "urn:schemas-microsoft-com:office:smarttags" />Zhengzhou University,Zhengzhou 450052,China)
Abstract
Objective:To study the relation between the expressions of nm23-H1 as well as MVD and SCT features in colorectal carcinoma with serosa invasion.
Methods:Relate to the various invasion depth of colorectal carcinoma in SCT features,analysis of the MVD and the expression of nm23-H1 in 42 cases was obtained by using immunohistochemical streptavidin peroxidase conjugate method.
Results:In the serosa-invasion group and the non-serosa-invasion group of 42 cases in SCT features,the microvessel densities was a remarkable difference (t.=-2.852,P=0.007) and the positive rates of nm23-H1 was no remarkable difference(x2=0.318,P=0.710)between them. The difference of microvessel densities between the nm23-H1-positive group and the nm23-H1-negative group was significant(t=-2.149,P=0.038). |