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大肠癌浆膜侵犯螺旋CT征象与MVD、nm23-H1表达间关系的研究

时间:2006-11-17 21:33:23  来源:  作者:

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Correlation between spiral CT features of serosa invasion and expression Of MVD and nm23H1 in colorectal carcinoma

 

张永高1  高剑波1  杨学华1  张谢夫2  张云汉3  1  陈学军1  周志刚1  杨晓鹏1  岳松伟1

1.郑州大学一附院放射科2.普外科3.病理科河南郑州 450052

ZHANG YonggaoGAO JianboYANG XuehuaZHANG XiefuZHANG YunhanGUO HuaCHEN XuejunZHOU ZhigangYANG XiaopengYUE Songwei

Department of Radiologythe First Affiliated Hospital of <?xml:namespace prefix = st1 ns = "urn:schemas-microsoft-com:office:smarttags" />Zhengzhou UniversityZhengzhou 450052China

 

Abstract

  ObjectiveTo study the relation between the expressions of nm23H1 as well as MVD and SCT features in colorectal carcinoma with serosa invasion.

  MethodsRelate to the various invasion depth of colorectal carcinoma in SCT featuresanalysis of the MVD and the expression of nm23H1 in 42 cases was obtained by using immunohistochemical streptavidin peroxidase conjugate method.

  ResultsIn the serosainvasion group and the nonserosainvasion group of 42 cases in SCT featuresthe microvessel densities was a remarkable difference t.=2.852P=0.007 and the positive rates of nm23H1 was no remarkable differencex2=0.318P=0.710between them. The difference of microvessel densities between the nm23H1positive group and the nm23H1negative group was significantt=2.149P=0.038.

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