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肝硬化CT分级方法研究

时间:2006-11-22 21:58:45  来源:  作者:

Method Study of CT Grade in Liver Cirrhosis<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

 

涂蓉 张阳德 伍保忠* 黄海伟* 郑妙琼*

TU Rong,ZHANG Yangde,WU Baozhong*,et al

 

Abstract

  Objective:A new method is designed for diagnosing liver cirrhosis through CT image of liver cirrhosis.

  Methods:The study were 50 hospitalized cases of liver cirrhosis which included 42 males and 8 females in gender,The mean age was 55.9 years old ranged from 34 to 79 years old.All of 50 subjects had plain CT and/or enhanced CT scanning and clinical materials.A new method for grading liver CT was studied by double-blind method and was used to grade the 50 cases with liver cirrhosis according to their CT images.To explore the effect of the CT grade,Comparisons were made for the CT grade to the Child-Pugh grade, and to therapy result and to prognosis of these 50 patients.

  Results:The correlation of the double-blind results were 0.89、0.93 and 0.96(P<0.0001).The correlation of liver CT grade and Child-Pugh grade was RS=0.8 (P<0.0001), which showed a significant association with prognosis (two-sides:P<0.0001).The level and the number of portal hypertension signs were increasing with CT grade from 1 to 4.

  Conclusion:CT grade which was according to hepatic CT sign and portal vein hypertension CT sign may be one of important indices available for assessment serious level and prognosis of liver cirrhosis.

  Key words:Liver cirrhosis CT grade Tomography,X-ray computed 

 

  虽然CT诊断肝硬化的a有无价值有限,但随着肝硬化程度的加重,CT征象越来越明显。那么,能否通过CT的形态学分级,对肝硬化的严重程度进行判断?这是对肝病施行内科、外科或介入治疗时共同关心的问题。虽然临床上诊断的方法较多[1-4],但未见通过CT分级进行预后估计的报道。该研究试图通过肝硬化CT的形态学改变,探索一种CT肝硬化分级诊断的方法和指标,并进行其临床应用价值研究。

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