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Comparison of Helical CT Pulmonary Angiography with Ventilation－Perfusion Scintigraphy on the Sensitivity and Specificity for Diagnosing Pulmonary Embolism：An Experiment Study
朱力1，郭玉林1，龚瑞1，陈勇1，郭佑民2
（1. 宁夏医学院附属医院放射科，银川 750004；2. 西安交通大学第一医院影像中心，西安 710061）
ZHU Li1，GUO Yu－lin1，GONG Rui1，CHEN Yong1，GUO You－min2
（1.Departmant of Radiology，the Affiliated Hospital of Ningxia Medical College，Yinchuan，750004；2.Imaging Center，No 1 Hospital，Jiaotong University，Xi’an，710061）
Abstract
Objective：To compare the accuracy of helical computer tomography pulmonary angiography （HCT2PA） with ventilation perfusion scintigraphy （ECTV － P） for diagnosing pulmonary embolism.
Methods：Eight canine pulmonary arteries were embolied with gelatin sponges under DSA guidance .Then the dogs underwent helical CT pulmonary angiography and ventilation － perfusion scintigraphy examination respectively. With anatomic findings as standard，the sensitivities and specificities diagnosing the lung embolism by both methods were compared.
Results：Thirty six segment and subsegment arteries emboli were found by anatomic dissection，30 embolized arteries were found by HCTPA，the diagnosing sensitivity and specificity were 75％ and 97.9％，respectively.The secondary affection of pulmonary parenchyma was also found .Thirty three dismatch regions were found by ECTV － Pexamination，the diagnosing sensitivity and specificity were 96％ and 90.6％，respectively.
Conclusion：Not only with relatively high diagnosing sensitivity and specificity，but with the action of diagnosing the secondary affection of pulmonary parenchyma，the HCTPA could be used as the first － line approach for diagnosing pulmonary embolism.
Key Words：pulmonary embolism；computer tomography；single photon emission computer tomography；canine | 
